Products for Research Use Only
RegisterLogin

CDKI-73

CAT: 0013-GTR19175039-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19175039-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CDKI-73 is a highly potent and selective CDK9 inhibitor (Ki = 4 nM) with significant toxicity toward chronic lymphocytic leukemia (CLL) cells in vitro. Its mechanism involves inducing apoptosis and synergizing with chemotherapeutics like cisplatin, highlighting its research utility in oncology and hematology for studying transcription-dependent cancers.
CAS Number
1421693-22-2
Product Name Alternative
CDK9, CDKI 73, CDKI73, CDKI-73, CDK7, CDK6, CDK4, CDK2, CLL, CDK1, CDK, Cyclin dependent kinase, AML, Apoptosis, Acute, inhibit, Inhibitor, LS007, LS-007, LS 007, low, myeloid, endosome, leukemia, toxicity
Field of Research
Cell Biology
Purity
95.88% (May vary between batches)
Solubility
DMSO:52 mg/mL (131.83 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (6.34 mM)
Smiles
CNc1nc (C) c (s1) -c1nc (Nc2cccc (c2) S (N) (=O) =O) ncc1F
Molecular Formula
C15H15FN6O2S2
Molecular Weight
394.45
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Asnuciclib

Asnuciclib is an organic molecular entity. It has a role as an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.

CAS Number1421693-22-2
PubChem CID71561915
IUPAC Name3-[[5-fluoro-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide
Molecular FormulaC15H15FN6O2S2
Molecular Weight394.5
XLogP2.2
Topological Polar Surface Area160
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity577
SMILES
CC1=C(SC(=N1)NC)C2=NC(=NC=C2F)NC3=CC(=CC=C3)S(=O)(=O)N
InChI
InChI=1S/C15H15FN6O2S2/c1-8-13(25-15(18-2)20-8)12-11(16)7-19-14(22-12)21-9-4-3-5-10(6-9)26(17,23)24/h3-7H,1-2H3,(H,18,20)(H2,17,23,24)(H,19,21,22)
InChIKey
GAIOPWBQKZMUNO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Asnuciclib
CAS: 1421693-22-2
CID: 71561915
Formula: C15H15FN6O2S2
MW: 394.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight394.5
XLogP32.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass394.06819425
Monoisotopic Mass394.06819425
Topological Polar Surface Area160 Ų
Heavy Atom Count26
Formal Charge0
Complexity577
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19211105-01CDKi Hydrochloride
GTR19208093-01CDKI-83
GTR19250150-01CDKI-IN-1
GTR19204104-01AC-73
GTR19239120-01α-Glucosidase-IN-73
GTR19258496-01NLRP3-IN-73
GTR19234096-01HDAC-IN-73
GTR19212342-01EGFR-IN-73
GTR19249305-01SKI-73
GTR19238984-01AChE-IN-73

Alternative Products

CatalogName
T14919-01CDKI-73
A21467-100Asnuciclib (CDKI-73) 100mg
A21467-10Asnuciclib (CDKI-73) 10mg
A21467-5Asnuciclib (CDKI-73) 5mg
A21467-25Asnuciclib (CDKI-73) 25mg
A21467-50Asnuciclib (CDKI-73) 50mg
A21467-2Asnuciclib (CDKI-73) 2mg
A21467-1Asnuciclib (CDKI-73) 1mg
A21467-10mM-DAsnuciclib (CDKI-73) 10mM * 1mL in DMSO
MBS5811396CDKi Hydrochloride

Popular Products