UT-34

• Target:

  Estrogen Receptor/ERR|||Androgen Receptor

• Related Pathways:

  Endocrinology/Hormones

• Purity:

  0.9812

• Bioactivity:

  UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader (IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prostate cancer efficacy.

• Smiles:

  C[C@](O)(Cn1cc(F)cn1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

• Molecular Formula:

  C15H12F4N4O2

• Molecular Weight:

  356.27

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2168525-92-4