UT-B-IN-1

CAT: 0931-MF-0146601-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0146601-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
892742-76-6
Target
Urea Transporter|||Others
Related Pathways
Others|||Membrane transporter/Ion channel
Bioactivity
UT-B-IN-1 (UTBINH-14) is a reversible, competitive, and selective inhibitor of the urea transporter-B (UT-B) with IC50 values of 10 nM and 25 nM for human and mouse UT-B, respectively. It exhibits low toxicity and superior selectivity against UT-B compared to UT-A isoforms, enhances urine production, and decreases urine concentration in mice, making it suitable for research on diuretic mechanisms.
Smiles
S(=O)(=O)(C1=C2N(C3=C(C(NCC4=CC=CS4)=N2)SC=C3)N=N1)C5=CC=C(CC)C=C5
Molecular Formula
C20H17N5O2S3
Molecular Weight
455.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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