UT-34

CAT: 1410-M22452-01Size: 1 gDry Ice: NoHazardous: No

1 gSelected

PRICE

AVAILABILITY

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

1 / 1

Description

UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader (IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prostate cancer efficacy. In LNCaP cells, UT-34 (3-10 µM; 24 hours) treatment inhibits the expression of PSA and FKBP5 and growth of LNCaP cells starting from 100 nM with maximum effect observed at 10 μM.

CAS Number

2168525-92-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

356.27

Molecular Formula

C15H12F4N4O2

Notes

Research use only, not for human use.

Receptor

Androgen receptor

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UT-34

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