MBM-55

• Target :

  Apoptosis|||Chk|||Akt|||GSK-3|||DYRK|||MAPK|||Aurora Kinase|||S6 Kinase|||CDK|||Bcr-Abl

• Related Pathways :

  Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||Apoptosis|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling|||MAPK|||Stem Cells

• Purity :

  0.9998

• Bioactivity :

  MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

• Smiles :

  CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1

• Molecular Formula :

  C28H27FN6O2

• Molecular Weight :

  498.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2083622-09-5