MBM-17

• Target:

  Aurora Kinase|||MAPK|||Apoptosis

• Related Pathways:

  Chromatin/Epigenetic|||Apoptosis|||MAPK|||Cell Cycle/Checkpoint

• Bioactivity:

  MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2, IC50 of 3 nM) . It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

• Smiles:

  O(CC1=CC=CC=C1)C=2C=C(C=3N4C(C=C(C=C4)C5=CN(CCN(C)C)N=C5)=NC3)C=CC2C(N)=O

• Molecular Formula:

  C28H28N6O2

• Molecular Weight:

  480.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2083621-90-1