MBM-17S

• Target :

  MAPK|||Aurora Kinase|||Apoptosis

• Related Pathways :

  MAPK|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Apoptosis

• Bioactivity :

  MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and apoptosis. It demonstrates antitumor activities without evident toxicity to mice.

• Smiles :

  O=C(CCC(O)=O)O.O=C(C1=C(OCC2=CC=CC=C2)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)C=C1)N.O=C(CCC(O)=O)O

• Molecular Formula :

  C36H40N6O10

• Molecular Weight :

  716.74

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2083621-91-2