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MBM-17S

CAT: 0931-T11959-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T11959-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2083621-91-2
Target
MAPK|||Aurora Kinase|||Apoptosis
Related Pathways
MAPK|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Apoptosis
Bioactivity
MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and apoptosis. It demonstrates antitumor activities without evident toxicity to mice.
Smiles
O=C(CCC(O)=O)O.O=C(C1=C(OCC2=CC=CC=C2)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)C=C1)N.O=C(CCC(O)=O)O
Molecular Formula
C36H40N6O10
Molecular Weight
716.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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