DRI-C21045

CAT: 0931-T11096-02Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T11096-02Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2101765-81-3

Target

NF-κB, TNF

Related Pathways

NF-κB, Apoptosis

Purity

0.981

Bioactivity

Dri-c21045 showed concentration-dependent inhibition of NF-kB activation and all CD40L induced by B cell proliferation with IC50 of 17.1 μM and 4.5 μM, respectively. Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein interaction (PPI) with IC50 of 0.17 μM.

Smiles

COC(=O)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc2cccc(c12)S(O)(=O)=O

Molecular Formula

C32H24N2O7S

Molecular Weight

580.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

8-(4'-(4-(Methoxycarbonyl)benzamido)-[1,1'-biphenyl]-4-carboxamido)naphthalene-1-sulfonic acid

CAS Number	2101765-81-3
PubChem CID	129275747
IUPAC Name	8-[[4-[4-[(4-methoxycarbonylbenzoyl)amino]phenyl]benzoyl]amino]naphthalene-1-sulfonic acid
Molecular Formula	C32H24N2O7S
Molecular Weight	580.6
XLogP	5.1
Topological Polar Surface Area	147
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	8
Heavy Atom Count	42
Formal Charge	0
Complexity	1050

SMILES

COC(=O)C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)NC4=CC=CC5=C4C(=CC=C5)S(=O)(=O)O

InChI

InChI=1S/C32H24N2O7S/c1-41-32(37)25-14-12-23(13-15-25)30(35)33-26-18-16-21(17-19-26)20-8-10-24(11-9-20)31(36)34-27-6-2-4-22-5-3-7-28(29(22)27)42(38,39)40/h2-19H,1H3,(H,33,35)(H,34,36)(H,38,39,40)

InChIKey

BZAWLSZPOBGURT-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2101765-81-3

CID: 129275747

Formula: C32H24N2O7S

MW: 580.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	580.6
XLogP3	5.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	8
Exact Mass	580.13042228
Monoisotopic Mass	580.13042228
Topological Polar Surface Area	147 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	1050
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
BUP06662-01	DRI-C21045
A18773-200	DRI-C21045 200mg
A18773-25	DRI-C21045 25mg
A18773-5	DRI-C21045 5mg
A18773-100	DRI-C21045 100mg
A18773-50	DRI-C21045 50mg
A18773-10	DRI-C21045 10mg
HY-P4157-01	FOXO4-DRI
HY-154822-01	DRI-C25441
MBS5820855	DRI-C21041

DRI-C21045

Chemical Information

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