DRI-C21045

• Target:

  NF-?B|||TNF

• Related Pathways:

  NF-?B|||Apoptosis

• Purity:

  0.981

• Bioactivity:

  Dri-c21045 showed concentration-dependent inhibition of NF-kB activation and all CD40L induced by B cell proliferation with IC50 of 17.1 ?M and 4.5 ?M, respectively. Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein interaction (PPI) with IC50 of 0.17 ?M.

• Smiles:

  COC (=O) c1ccc (cc1) C (=O) Nc1ccc (cc1) -c1ccc (cc1) C (=O) Nc1cccc2cccc (c12) S (O) (=O) =O

• Molecular Formula:

  C32H24N2O7S

• Molecular Weight:

  580.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2101765-81-3