DRI-C21045

• Target :

  NF-?B|||TNF

• Related Pathways :

  NF-?B|||Apoptosis

• Purity :

  0.981

• Bioactivity :

  Dri-c21045 showed concentration-dependent inhibition of NF-kB activation and all CD40L induced by B cell proliferation with IC50 of 17.1 ?M and 4.5 ?M, respectively. Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein interaction (PPI) with IC50 of 0.17 ?M.

• Smiles :

  COC(=O)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc2cccc(c12)S(O)(=O)=O

• Molecular Formula :

  C32H24N2O7S

• Molecular Weight :

  580.61

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2101765-81-3