AMG 487

CAT: 0931-T10297L-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T10297L-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
473719-41-4
Target
CXCR
Related Pathways
GPCR/G Protein|||Autophagy|||Immunology/Inflammation
Purity
0.9989
Bioactivity
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
Smiles
CCOc1ccc(cc1)-n1c(nc2ncccc2c1=O)[C@@H](C)N(Cc1cccnc1)C(=O)Cc1ccc(OC(F)(F)F)cc1
Molecular Formula
C32H28F3N5O4
Molecular Weight
603.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS6233371-01IFIT3 (Interferon-induced Protein with Tetratricopeptide Repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60kD Protein, IFI-60K, Interferon-induced Protein with Tetratricopeptide Repeats 4, IFIT-4, Retinoic Acid-induced Gene G-Protein, P60, RIG-G, CIG
MBS6235285-01SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Alpha-SGT, Vpu-binding protein, UBP, SGT, SGT1) (MaxLight 750)
MBS6235917-01TSPAN1 (Tetraspanin-1, Tetraspan NET-1, Tetraspanin TM4-C) (MaxLight 750)
MBS6235920-01TSPAN8 (Tetraspanin-8, Tspan-8, Transmembrane 4 Superfamily Member 3, TM4SF3, Tumor-associated Antigen CO-029) (MaxLight 750)
MBS6241195-01TSPAN2 (Tetraspanin 2, 6330415F13Rik, FLJ12082, TSN2, TSPAN-2) (MaxLight 750)
MBS6241196-01TSPAN32 (Tetraspanin 32, FLJ17158, FLJ97586, MGC22455, PHEMX, PHMX, TSSC6) (MaxLight 750)
MBS6247488-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (AP)
MBS6249514-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (FITC)
MBS6252216-01Tetrahydrocannabinol (THC) (PE)

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