UK-124114

• Target:

  GABA Receptor|||Others

• Related Pathways:

  Neuroscience|||Others|||Membrane transporter/Ion channel

• Purity:

  0.9944

• Bioactivity:

  UK-124114 (Selamectin) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 ?g/ml) shows the effect of growth inhibition.

• Smiles:

  O[C@@]1\2[C@]3 (C (=NO) C (C) =C[C@]1 (C (=O) O[C@@]4 (C[C@@]5 (O[C@@H] ([C@@H] (C) CC5) [C@H]6CCCCC6) O[C@@] (C4) (C/C=C (\C) /[C@@H] (O[C@H]7C[C@H] (OC) [C@@H] (O) [C@H] (C) O7) [C@@H] (C) /C=C\C=C2\CO3) [H]) [H]) [H]) [H]

• Molecular Formula:

  C43H63NO11

• Molecular Weight:

  769.96

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  165108-07-6