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HG6-64-1

CAT: 0804-HY-12291-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12291-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1) ; has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells.
CAS Number
1315329-43-1
Product Name Alternative
HMSL 10017-101-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HG6-64-1.html
Purity
99.69
Solubility
DMSO : 75 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(/C=C/C4=CN=C(NC=C5)C5=C4OC)=C3
Molecular Formula
C32H34F3N5O2
Molecular Weight
577.64
Precautions
H302, H315, H319, H335
References & Citations
[1]WO 2011090738 A2
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
B-Raf

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Alternative Products

CatalogName
BA6533-5HG6-64-1
A16022-50HG6-64-1 50mg
A16022-25HG6-64-1 25mg
A16022-2HG6-64-1 2mg
A16022-100HG6-64-1 100mg
A16022-10HG6-64-1 10mg
A16022-5HG6-64-1 5mg

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