HDAC6-IN-64

• Description:

  HDAC6-IN-64 (Compound 8) is a HDAC6 inhibitor with an IC50 of 11.9 nM. HDAC6-IN-64 has poor cell permeability. HDAC6-IN-64 can be used for chemotherapy of cancers like NSCLC research[1].

• UNSPSC:

  12352005

• Target:

  HDAC

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics

• Field of Research:

  Cancer

• Smiles:

  O=C(C1=CC=C(C=C1)CN2C(N(C(C3=CC=CC=C32)=O)CCC4=CC=CC=C4)=O)NNCC

• Molecular Formula:

  C26H26N4O3

• Molecular Weight:

  442.51

• References & Citations:

  [1]Huang HC, et al. Establishing a noncanonical zinc-binding group as a selective histone deacetylase inhibitor and possible novel anticancer agent. Bioorg Chem. 2025 Aug 27;165:108917

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  HDAC1; HDAC6

• CAS Number:

  2837128-29-5