BVDU 5?-Triphosphate

• Target:

  DNA/RNA Synthesis|||HSV

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Microbiology/Virology

• Bioactivity:

  BVDU 5?-Triphosphate is an antiviral agent labeled with 5?-Triphosphate that specifically targets viral DNA polymerase. It exhibits outstanding selectivity for varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) owing to its phosphorylation by the virus-specific thymidine kinase.

• Smiles:

  O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C2)C=C(/C=C/Br)C(=O)N1

• Molecular Formula:

  C11H16BrN2O14P3

• Molecular Weight:

  573.08

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  77222-61-8