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LX-1031

CAT: 0804-HY-13041-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13041-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally.
CAS Number
945976-76-1
UNSPSC
12352005
Target
Tryptophan Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/LX-1031.html
Purity
99.14
Solubility
DMSO : ≥ 34 mg/mL
Smiles
NC1=NC(C2=CC=C(C=C2)C[C@@H](C(O)=O)N)=CC(O[C@H](C3=CC=C(C4=CC(OC)=CC=C4)C=C3)C(F)(F)F)=N1
Molecular Formula
C28H25F3N4O4
Molecular Weight
538.52
References & Citations
[1]Camilleri M. LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin. Neurogastroenterol Motil. 2011 Mar;23 (3) :193-200.|[2]Camilleri M. LX-1031, a tryptophan 5-hydroxylase inhibitor that reduces 5-HT levels for the potential treatment of irritable bowel syndrome. IDrugs. 2010 Dec;13 (12) :921-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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Alternative Products

CatalogName
M16780-01LX-1031
A11479-2LX-1031 2mg
A11479-100LX-1031 100mg
A11479-25LX-1031 25mg
A11479-10LX-1031 10mg
A11479-50LX-1031 50mg
A11479-5LX-1031 5mg
A11479-1LX-1031 1mg
A11479-10mM-DLX-1031 10mM * 1mL in DMSO
EUA20371-01HMR 1031

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