LX-3

LX-3

• CAS Number: 380645-50-1
• UNSPSC Description: LX-3 is a selective activator of the p38 MAPK signaling pathway and activates EGFP reporter genes that are silenced by DNA methylation, such as TNF, EGR1, LY6K, and ISG20[1].
• Target Antigen: p38 MAPK
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/lx-3.html
• Smiles: BrC1=CC=C(C(CN2C3=NC(C4=CC=CS4)=NN3C5=CC=CC=C25)=O)C=C1
• Molecular Weight: 437.31
• References & Citations: [1]Li X, et al., Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem. 2018 May 11;293(19):7423-7436.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported