BACE, phosphorylated (Ser498) (Beta-secretase 1, Beta-site APP Cleaving Enzyme 1, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Aspartyl Protease 2, Asp 2, ASP2, Membrane-associated Aspartic Protease 2, Memapsin-2, BACE1, BACE, KIAA1149)
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Catalog number
MBS630050
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Price
Please ask
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Size
0.2 mL
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Products_type
Antibody
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Products_short_name
[BACE]
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Products_name_syn
[Anti -BACE, phosphorylated (Ser498) (Beta-secretase 1, Beta-site APP Cleaving Enzyme 1, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Aspartyl Protease 2, Asp 2, ASP2, Membrane-associated Aspartic Protease 2, Memapsin-2, BACE1, BACE, KIAA1149)]
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Other_names
[BacE]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Recognizes human BACE when phosphorylated at Ser498.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in PBS, 0.09% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
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Description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
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Gene target
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Gene symbol
BACE1, APP-DT, BACE1-AS, APP, PABPC4, NAE1
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Short name
BACE, phosphorylated (Ser498) (Beta-secretase 1, Beta-site APP Cleaving Enzyme 1, Beta-site Amyloid Protein Cleaving Enzyme 1, Aspartyl Protease 2, Asp 2, ASP2, -associated Aspartic Protease 2, Memapsin-2, BACE1, BACE, KIAA1149)
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Technique
Enzyme, enzymes
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Host
Rabbit
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Isotype
IgG
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Alternative name
BACE, phosphorylated (Ser498) (b-secretase 1, b-site amyloid beta (A4) precursor protein Cleaving Enzyme 1, b-site Amyloid Precursor Protein Cleaving Enzyme 1, Aspartyl Protease 2, L-aspartic acid 2, ASP2, Membrane-associated Aspartic Protease 2, Memapsin-2, BACE1, BACE, KIAA1149)
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Alternative technique
enzymes
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Alternative to gene target
amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene name
beta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year
1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
APP divergent transcript
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Locus
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Discovery year
2020-06-12
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Classification
Gene info
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Identity
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Gene
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Long gene name
BACE1 antisense RNA
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Synonyms gene
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Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year
2009-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
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