BACE, Asp2 (Beta-secretase 1, Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE1, KIAA1149)
#
-
Catalog numberMBS633019
-
Price:
-
Size5x0.1 mg
-
-
Products_typeAntibody
-
Products_short_name[BACE, Asp2]
-
Products_name_syn[Anti -BACE, Asp2 (Beta-secretase 1, Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE1, KIAA1149)]
-
Other_names[beta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]
-
Other_gene_names[BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2]
-
ClonalityMonoclonal
-
Clone[11C83]
-
ReactivityHuman
-
SpecificityRecognizes human BACE, asp2.
-
PurityAffinity Purified Purified by immunoaffinity chromatography.
-
FormSupplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
-
Storage_stabilityLyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Â
-
Tested_applicationELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
-
DescriptionEnzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
-
Gene target
-
Gene symbolBACE1, APP-DT, BACE1-AS, APP, PABPC4, NAE1
-
Short nameBACE, Asp2 (Beta-secretase 1, Aspartyl Protease 2, ASP2, Asp 2, Beta-site Amyloid Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, Memapsin-2, -associated Aspartic Protease 2, BACE1, KIAA1149)
-
TechniqueEnzyme, enzymes
-
HostMouse
-
IsotypeIgG1
-
Alternative nameBACE, Asp2 (b-secretase 1, Aspartyl Protease 2, ASP2, L-aspartic acid 2, b-site Amyloid Precursor Protein Cleaving Enzyme 1, b-site amyloid beta (A4) precursor protein Cleaving Enzyme 1, Memapsin-2, Membrane-associated Aspartic Protease 2, BACE1, KIAA1149)
-
Alternative techniqueenzymes
-
Alternative to gene targetamyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
-
Gene info
-
Identity
-
Gene
-
Long gene namebeta-secretase 1
-
Synonyms gene
-
Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
-
GenBank acession
-
Locus
-
Discovery year1999-10-29
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Peptidase family A1
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameAPP divergent transcript
-
Locus
-
Discovery year2020-06-12
-
Classification
- Divergent transcripts
Gene info
-
Identity
-
Gene
-
Long gene nameBACE1 antisense RNA
-
Synonyms gene
-
Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year2009-07-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Antisense RNAs
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameamyloid beta precursor protein
-
Synonyms gene
-
Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namepoly(A) binding protein cytoplasmic 4
-
Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-12-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameNEDD8 activating enzyme E1 subunit 1
-
Synonyms gene
-
Synonyms gene name
- amyloid beta precursor protein binding protein 1, 59kDa
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-01-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Ubiquitin like modifier activating enzymes
-
VEGA ID