BACE1 (Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE 1, APP beta Secretase, Aspartyl Protease 2, Asp 2, ASP2, Asp-2, Beta Secretase 1, Beta Secretase, Beta Site Amyloid beta A4 Precursor Protein Cleaving Enzy
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Catalog numberMBS607346
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Price:
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Size5x0.1 mL
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Products_typeAntibody
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Products_short_name[BACE1]
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Products_name_syn[Anti -BACE1 (Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE 1, APP beta Secretase, Aspartyl Protease 2, Asp 2, ASP2, Asp-2, Beta Secretase 1, Beta Secretase, Beta Site Amyloid beta A4 Precursor Protein Cleaving Enzy]
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Other_names[beta-secretase 1 isoform F; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]
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Other_gene_names[BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2]
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ClonalityMonoclonal
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Clone[10E7]
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ReactivityHuman, Mouse, Rat
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SpecificityRecognizes human BACE. Species crossreactivity: mouse, rat.
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FormSupplied in 10 mM sodium HEPES (pH 7.5), 150mM NaCl, 100ug/ml BSA and 50% glycerol.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionEnzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
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Gene target
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Gene symbolAPP-DT, BACE1, APP, PABPC4, NAE1, BACE1-AS
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Short nameBACE1 (Beta-site Amyloid Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE 1, APP beta Secretase, Aspartyl Protease 2, Asp 2, ASP2, Asp-2, Beta Secretase 1, Beta Secretase, Beta Site Amyloid beta A4 Protein Cleaving Enzy
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TechniqueEnzyme, enzymes
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HostRabbit
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IsotypeIgG
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Alternative nameBACE1 (b-site Amyloid Precursor Protein Cleaving Enzyme 1, b-site amyloid beta (A4) precursor protein Cleaving Enzyme 1, BACE 1, amyloid beta (A4) precursor protein b Secretase, Aspartyl Protease 2, L-aspartic acid 2, ASP2, L-aspartic acid-2, b Secretase 1, b Secretase, b Site Amyloid b A4 Precursor Protein Cleaving Enzy
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Alternative techniqueenzymes
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Alternative to gene targetamyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene nameAPP divergent transcript
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Locus
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Discovery year2020-06-12
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namebeta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
- Peptidase family A1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameamyloid beta precursor protein
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Synonyms gene
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Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepoly(A) binding protein cytoplasmic 4
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Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNEDD8 activating enzyme E1 subunit 1
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Synonyms gene
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Synonyms gene name
- amyloid beta precursor protein binding protein 1, 59kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ubiquitin like modifier activating enzymes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBACE1 antisense RNA
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Synonyms gene
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Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year2009-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID