BACE, Asp2 (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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Catalog numberMBS620654
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PricePlease ask
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[BACE, Asp2]
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Products_name_syn[Anti -BACE, Asp2 (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)]
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Other_names[beta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]
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Other_gene_names[BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2]
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ClonalityPolyclonal
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ReactivityMouse
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SpecificityRecognizes mouse BACE/Asp2. No significant sequence homology exists with BACE2/Aps1, a homolog of BACE, or other Asps.
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PurityAffinity Purified Purified by immunoaffinity chromatography.
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FormSupplied as a liquid in PBS, pH 7.4, 0.1% BSA, 40% glycerol.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationELISA (EL/EIA), Western Blot (WB)
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DescriptionEnzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbolAPP-DT, BACE1, APP, PABPC4, NAE1
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Short nameBACE, Asp2 (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
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TechniqueEnzyme, enzymes
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HostRabbit
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IsotypeIgG
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Alternative nameBACE, Asp2 (Memapsin2, b-site amyloid beta (A4) precursor protein Cleaving Enzyme, Aspartyl Protease 2)
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Alternative techniqueenzymes
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Alternative to gene targetamyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene nameAPP divergent transcript
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Locus
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Discovery year2020-06-12
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namebeta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
- Peptidase family A1
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameamyloid beta precursor protein
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Synonyms gene
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Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepoly(A) binding protein cytoplasmic 4
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Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNEDD8 activating enzyme E1 subunit 1
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Synonyms gene
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Synonyms gene name
- amyloid beta precursor protein binding protein 1, 59kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ubiquitin like modifier activating enzymes
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VEGA ID