BACE1 (Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE 1, APP beta Secretase, Aspartyl Protease 2, Asp 2, ASP2, Asp-2, Beta Secretase 1, Beta Secretase, Beta Site Amyloid beta A4 Precursor Protein Cleaving Enzy
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Catalog number
MBS607346
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Price
Please ask
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Size
0.02 mL
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Products_type
Antibody
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Products_short_name
[BACE1]
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Products_name_syn
[Anti -BACE1 (Beta-site Amyloid Precursor Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE 1, APP beta Secretase, Aspartyl Protease 2, Asp 2, ASP2, Asp-2, Beta Secretase 1, Beta Secretase, Beta Site Amyloid beta A4 Precursor Protein Cleaving Enzy]
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Other_names
[beta-secretase 1 isoform F; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]
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Other_gene_names
[BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2]
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Clonality
Monoclonal
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Clone
[10E7]
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Reactivity
Human, Mouse, Rat
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Specificity
Recognizes human BACE. Species crossreactivity: mouse, rat.
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Form
Supplied in 10 mM sodium HEPES (pH 7.5), 150mM NaCl, 100ug/ml BSA and 50% glycerol.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Immunoprecipitation (IP)
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Description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
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Gene target
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Gene symbol
APP-DT, BACE1, APP, PABPC4, NAE1, BACE1-AS
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Short name
BACE1 (Beta-site Amyloid Protein Cleaving Enzyme 1, Beta-site APP Cleaving Enzyme 1, BACE 1, APP beta Secretase, Aspartyl Protease 2, Asp 2, ASP2, Asp-2, Beta Secretase 1, Beta Secretase, Beta Site Amyloid beta A4 Protein Cleaving Enzy
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Technique
Enzyme, enzymes
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Host
Rabbit
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Isotype
IgG
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Alternative name
BACE1 (b-site Amyloid Precursor Protein Cleaving Enzyme 1, b-site amyloid beta (A4) precursor protein Cleaving Enzyme 1, BACE 1, amyloid beta (A4) precursor protein b Secretase, Aspartyl Protease 2, L-aspartic acid 2, ASP2, L-aspartic acid-2, b Secretase 1, b Secretase, b Site Amyloid b A4 Precursor Protein Cleaving Enzy
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Alternative technique
enzymes
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Alternative to gene target
amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722
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Gene info
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Identity
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Gene
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Long gene name
APP divergent transcript
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Locus
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Discovery year
2020-06-12
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Classification
Gene info
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Identity
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Gene
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Long gene name
beta-secretase 1
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Synonyms gene
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Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
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GenBank acession
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Locus
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Discovery year
1999-10-29
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
BACE1 antisense RNA
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Synonyms gene
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Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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Locus
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Discovery year
2009-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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