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Products_type
Recombinant Protein
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Products_short_name
[FLT3 Ligand]
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Products_name_syn
[Human FLT3 Ligand Protein, mFc-His Tag; FLT3LG; FL; FLT3L; Flt3 ligand]
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Other_names
[fms-related tyrosine kinase 3 ligand; Fms-related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; flt3 ligand; fms-related tyrosine kinase 3 ligand; SL cytokine]
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Products_gene_name
[FLT3]
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Other_gene_names
[FLT3LG; FLT3LG; FL; FLT3L; Flt3 ligand; Flt3L]
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Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
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Form
Lyophilized from sterile PBS, pH 7.4. Normally 5%-40% trehalose is added as protectants before lyophilization.
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Storage_stability
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)Shipping: Blue Ice
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Tested_application
Western Blot (WB), ELISA (EIA)
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Conjugated
The polyhistidine (6xHis) tag or Histidine Epitope Tag (HIS Tag, 6XHIS Tag with Histidine (abbreviated as His or H; encoded by the codons CAU and CAC) is an α-amino acid that is used in the biosynthesis of proteins. It is the most used tag for purification by Affinity Chromatography (IMAC). The pentadentate chelator is the best chelator in Immobilized Metal ion Affinity chromatography (IMAC) for the6xhis-tagged proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FLT3
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Short name
Recombinant FLT3 Ligand protein with C-terminal mouse Fc tag
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Technique
Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
HEK293 cells
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Label
tag
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Species
Mouse, Humans, Mouses
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Alternative name
Rec. H. sapiens fms-related tyrosine kinase 3 Ligand protein including C-terminal mouse fragment c and 6xHis detection labelled
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Alternative technique
rec, murine
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Alternative to gene target
fms-related tyrosine kinase 3, CD135 and FLK-2 and FLK2 and STK1, FLT3 and IDBG-19891 and ENSG00000122025 and 2322, transferase activity, nuclei, Flt3 and IDBG-209045 and ENSMUSG00000042817 and 14255, BT.28173 and IDBG-630678 and ENSBTAG00000018572 and 512700
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