Recombinant human PD-L1 protein with C-terminal mouse Fc and 6xHis tag
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Catalog numberMBS188079
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PricePlease ask
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SizeINQUIRE
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Products_typeRecombinant Protein
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Products_short_name[PD-L1]
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Products_name_syn[Human PD-L1 Protein, mFc-His tag; PD-L1; CD274; B7-H1; PDCD1L1; PDCD1LG1]
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Other_names[programmed cell death 1 ligand 1 isoform b; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; CD274 molecule; B7 homolog 1]
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Products_gene_name[PD-L1]
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Other_gene_names[CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; B7H1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1]
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PurityThe purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
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FormLyophilized from sterile PBS, pH 7.4. Normally 5%-30% trehalose is added as protectants before lyophilization.
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Storage_stabilityStore at -80 degree C for 12 months (Avoid repeated freezing and thawing)Shipping: Blue Ice
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Tested_applicationWestern Blot (WB), ELISA (EIA)
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ConjugatedThe polyhistidine (6xHis) tag or Histidine Epitope Tag (HIS Tag, 6XHIS Tag with Histidine (abbreviated as His or H; encoded by the codons CAU and CAC) is an α-amino acid that is used in the biosynthesis of proteins. It is the most used tag for purification by Affinity Chromatography (IMAC). The pentadentate chelator is the best chelator in Immobilized Metal ion Affinity chromatography (IMAC) for the6xhis-tagged proteins.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCD274, ENPP2, MTA2, MICALL1, IGKV1-16, ZBTB4, UCHL1, COLEC10, PDCD1, FAM71F1
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Short nameRecombinant PD-L1 protein with C-terminal mouse Fc tag
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TechniqueRecombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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HostHEK293 cells
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Labeltag
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SpeciesMouse, Humans, Mouses
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Alternative nameRec. H. sapiens PD-L1 protein including C-terminal mouse fragment c and 6xHis detection labelled
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Alternative techniquerec, murine
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Gene info
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Identity
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Gene
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Long gene nameCD274 molecule
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Synonyms gene
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Synonyms gene name
- programmed cell death 1 ligand 1
- CD274 antigen
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
- C2-set domain containing
- V-set domain containing
- B7 family
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 2
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-08-10
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Entrez gene record
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Pubmed identfication
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Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemetastasis associated 1 family member 2
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Synonyms gene
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Synonyms gene name
- metastasis associated gene family, member 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-05-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- GATA zinc finger domain containing
- NuRD complex subunits
- Myb/SANT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMICAL like 1
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Synonyms gene name
- MICAL-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-11-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- LIM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1-16
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger and BTB domain containing 4
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BTB domain containing
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameubiquitin C-terminal hydrolase L1
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Synonyms gene
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Synonyms gene name
- ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ubiquitin C-terminal hydrolases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecollectin subfamily member 10
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Synonyms gene name
- collectin sub-family member 10 (C-type lectin)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-11
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Entrez gene record
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Pubmed identfication
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Classification
- Collectins
- C-type lectin domain containing
- Complement system activation components
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprogrammed cell death 1
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Synonyms gene
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Synonyms gene name
- systemic lupus erythematosus susceptibility 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-05-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefamily with sequence similarity 71 member F1
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Synonyms gene
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Synonyms gene name
- family with sequence similarity 137, member A
- family with sequence similarity 71, member F1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-07-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data