Mouse Monoclonal [clone PAG-C1] (IgG2b) to Human PAG1 / PAG

• Catalog number
  MBS245321
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [PAG1 / PAG]
• Products_name_syn
  [Anti-PAG1 / PAG Antibody (C-Terminus, clone PAG-C1) IHC-plus; PAG1; Csk-binding protein; CBP; PAG; Human PAG1; PAG]
• Other_names
  [phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Phosphoprotein associated with glycosphingolipid-enriched microdomains 1; phosphoprotein associated with glycosphingolipid-enriched microdomains 1; Csk-binding protein; transmembrane phosphoprotein Cbp; transmembrane adapter protein PAG; transmembrane adaptor protein PAG; phosphoprotein associated with glycosphingolipid microdomains 1; phosphoprotein membrane anchor with glycosphingolipid microdomains 1; Csk-binding protein; Transmembrane adapter protein PAG; Transmembrane phosphoprotein Cbp]
• Products_gene_name
  [PAG1]
• Products_gene_name_syn
  [PAG]
• Other_gene_names
  [PAG1; PAG1; CBP; PAG; CBP; PAG]
• Clonality
  Monoclonal
• Clone
  [PAG-C1]
• Reactivity
  Bovine, Human, Mouse, Rat
• Specificity
  Recognizes an epitope located in the C-terminal domain of Csk-binding protein (Cbp / PAG), a 46 kD ubiquitously expressed transmembrane adaptor protein present in membrane rafts (glycosphingolipid-enriched microdomains), which however migrates on SDS PAGE gels anomalously as an 80 kD molecule.
• Purity
  Protein A Purified
• Form
  PBS, 15 mM sodium azide, approx., pH 7.4.
• Concentration
  1 mg/ml
• Storage_stability
  +4 degree C or -20 degree C, Avoid repeated freezing and thawing.
• Tested_application
  Immunohistochemistry (IHC - Paraffin), Immunoprecipitation (IP)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Monoclonal   PAG-C1]   IgG2b   PAG1   PAG  
• Gene symbol
  PAG1, SNAR-C1, TRGC1, PFDN4, TNS2, ARHGAP4, MAGEC1, SERPING1, PLAAT1
• Short name
  Mouse Monoclonal [clone PAG-C1] (IgG2b) PAG1 / PAG
• Technique
  Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2b, IgG2b
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse monoclonal [clonality PAG-C1] (IgG2b) to H. sapiens phosphoprotein associated with glycosphin this GO lipid microdomains 1 / PAG
• Alternative technique
  murine
• Alternative to gene target
  phosphoprotein associated with glycosphin this GO lipid microdomains 1, PAG1 and IDBG-26542 and ENSG00000076641 and 55824, SH2 domain binding, Plasma membranes, Pag1 and IDBG-131044 and ENSMUSG00000027508 and 94212, PAG1 and IDBG-644850 and ENSBTAG00000014026 and 614460
• Clone name
  PAG-C1

Gene info

• Identity
  HGNC:30043
• Gene
  PAG1
• Long gene name
  phosphoprotein membrane anchor with glycosphingolipid microdomains 1
• Synonyms gene name
  • phosphoprotein associated with glycosphingolipid microdomains 1
• Synonyms
  • PAG
  • CBP
• Synonyms name
  • Csk-binding protein
  • transmembrane adaptor protein PAG
• GenBank acession
  • AF240634
• Locus
  8q21.13
• Discovery year
  2005-04-25
• Entrez gene record
  55824
• Pubmed identfication
  • 10790433
• RefSeq identity
  • NM_018440
• VEGA ID
  OTTHUMG00000164592

Gene info

• Identity
  HGNC:34319
• Gene
  SNAR-C1
• Long gene name
  small NF90 (ILF3) associated RNA C1
• Synonyms gene name
  • small ILF3/NF90-associated RNA C1
• GenBank acession
  • EU071066
• Locus
  19q13.32
• Discovery year
  2008-07-03
• Entrez gene record
  100170225
• Pubmed identfication
  • 17855395
• RefSeq identity
  • NR_024220
• Classification
  • Small NF90 (ILF3) associated RNAs

Gene info

• Identity
  HGNC:12275
• Gene
  TRGC1
• Long gene name
  T cell receptor gamma constant 1
• Synonyms gene
  • TCRGC1
• Synonyms gene name
  • TCRGC1
• Synonyms
  • C1
• Synonyms name
  • T-cell receptor, gamma, constant region C1
• GenBank acession
  • M14996
• Locus
  7p14.1
• Discovery year
  1989-05-30
• Entrez gene record
  6966
• Pubmed identfication
  • 2879283
• RefSeq identity
  • NG_001336
• Classification
  • T cell receptor gamma locus at 7p14
• VEGA ID
  OTTHUMG00000155219

Gene info

• Identity
  HGNC:8868
• Gene
  PFDN4
• Long gene name
  prefoldin subunit 4
• Synonyms gene name
  • prefoldin 4
• Synonyms
  • PFD4
  • C-1
  • C1
• GenBank acession
  • U41816
• Locus
  20q13.2
• Discovery year
  1998-08-06
• Entrez gene record
  5203
• Pubmed identfication
  • 9630229
  • 8744932
• RefSeq identity
  • NM_002623
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000032775

Gene info

• Identity
  HGNC:19737
• Gene
  TNS2
• Long gene name
  tensin 2
• Synonyms gene
  • TENC1
• Synonyms gene name
  • tensin like C1 domain-containing phosphatase
  • tensin like C1 domain containing phosphatase (tensin 2)
• Synonyms
  • KIAA1075
  • C1-TEN
• GenBank acession
  • AF518729
• Locus
  12q13.13
• Discovery year
  2002-12-09
• Entrez gene record
  23371
• RefSeq identity
  • NM_170754
• Classification
  • PTEN protein phosphatases
  • SH2 domain containing
  • C2 tensin-type domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169730

Gene info

• Identity
  HGNC:674
• Gene
  ARHGAP4
• Long gene name
  Rho GTPase activating protein 4
• Synonyms
  • KIAA0131
  • C1
  • p115
  • RhoGAP4
  • SrGAP4
• Synonyms name
  • Rho-GAP hematopoietic protein C1
• GenBank acession
  • X78817
• Locus
  Xq28
• Discovery year
  1997-08-28
• Entrez gene record
  393
• Pubmed identfication
  • 8570618
• RefSeq identity
  • NM_001666
• Classification
  • AH/BAR family Rho GTPase activating proteins
  • F-BAR domain containing
• VEGA ID
  OTTHUMG00000024226
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6812
• Gene
  MAGEC1
• Long gene name
  MAGE family member C1
• Synonyms gene name
  • melanoma antigen family C1
• Synonyms
  • MAGE-C1
  • CT7
  • MGC39366
  • CT7.1
• Synonyms name
  • cancer/testis antigen family 7, member 1
• GenBank acession
  • AF064589
• Locus
  Xq27.2
• Discovery year
  1999-04-23
• Entrez gene record
  9947
• Pubmed identfication
  • 9485030
  • 9618514
• RefSeq identity
  • NM_005462
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000022569
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:1228
• Gene
  SERPING1
• Long gene name
  serpin family G member 1
• Synonyms gene
  • C1NH
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
• Synonyms
  • C1IN
  • C1-INH
  • HAE1
  • HAE2
  • C1INH
• Synonyms name
  • plasma protease C1 inhibitor
  • angioedema, hereditary
  • C1-inhibitor
• GenBank acession
  • X54486
• Locus
  11q12.1
• Discovery year
  2001-06-22
• Entrez gene record
  710
• Pubmed identfication
  • 2026152
  • 24172014
• RefSeq identity
  • NM_000062
• Classification
  • Complement system regulators and receptors
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150304
• Locus Specific Databases
  • SERPING1base: Mutation registry for Hereditary angioedema
  • LRG_105

Gene info

• Identity
  HGNC:14922
• Gene
  PLAAT1
• Long gene name
  phospholipase A and acyltransferase 1
• Synonyms gene
  • HRASLS
• Synonyms gene name
  • HRAS like suppressor
• Synonyms
  • H-REV107
  • HRASLS1
  • A-C1
  • PLA/AT1
  • PLAAT-1
• Synonyms name
  • phospholipase A/acyltransferase 1
• GenBank acession
  • AB030816
• Locus
  3q29
• Discovery year
  2001-04-10
• Entrez gene record
  57110
• Pubmed identfication
  • 21880860
• Classification
  • Phospholipase A and acyltransferase family
• VEGA ID
  OTTHUMG00000156104

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