Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor)
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Catalog number
MBS602739
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[Integrin alphaV beta3]
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Products_name_syn
[Anti -Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor)]
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Other_names
[integrin beta-3; integrin beta-3; beta3 integrin; integrin beta 3; glycoprotein GPIIIa]
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Other_gene_names
[ITGB3; CD61]
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Clonality
Monoclonal
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Clone
[6A560]
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Reactivity
Human
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Specificity
Recognizes human alphav beta3 integrin
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Purity
Affinity Purified Purified by Protein G affinity chromatography
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Form
Supplied as a liquid in PBS, containing 0.02% sodium azide and 0.1% BSA
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
ITGB3, ITGAV
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Short name
Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor)
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Host
Mouse
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Isotype
IgG1
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Alternative name
Integrin alphaV beta3 (CD51/CD61, RGD-dependent Vitronectin Receptor)
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Gene info
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Identity
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Gene
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Long gene name
integrin subunit beta 3
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Synonyms gene
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Synonyms gene name
- integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
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Synonyms
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Synonyms name
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Locus
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Discovery year
1988-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Integrin beta subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
integrin subunit alpha V
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Synonyms gene
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Synonyms gene name
- antigen identified by monoclonal antibody L230
- vitronectin receptor
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- integrin, alpha V
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Synonyms
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Locus
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Discovery year
1988-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Integrin alpha subunits
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VEGA ID
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