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Products_type
Antibody
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Products_short_name
[Integrin alphaV beta3]
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Products_name_syn
[Anti -Integrin alphaV beta3 (Integrin alpha V, Integrin alpha-V, ITGAV, Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, CD51, CD51 Antigen, CD61, GP3A, GPIIIa, Msk8, Platelet Membrane Glycoprotein IIIa, Vitronectin Receptor a]
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Other_names
[integrin beta-3; integrin beta-3; beta3 integrin; integrin beta 3; glycoprotein GPIIIa]
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Other_gene_names
[ITGB3; CD61]
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Clonality
Monoclonal
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Clone
[BV3]
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Reactivity
Human
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Specificity
Recognizes human Integrin alphaV beta3 present on human endothelium cells.
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Purity
Purified Purified
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Form
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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Description
The Integrin alphaV beta3 (Integrin alpha V, Integrin alpha-V, ITGAV, Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, CD51, CD51 Antigen, CD61, GP3A, GPIIIa, Msk8, Platelet Glycoprotein IIIa, Vitronectin Receptor a is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
ITGB3, ITGAV
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Short name
Integrin alphaV beta3 (Integrin alpha V, Integrin alpha-V, ITGAV, Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, CD51, CD51 Antigen, CD61, GP3A, GPIIIa, Msk8, Platelet Glycoprotein IIIa, Vitronectin Receptor a
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Technique
antigen, antigenes
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Host
Mouse
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Isotype
IgG1
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Alternative name
Integrin alphaV beta3 (Integrin a V, Integrin a-V, integrin, alpha V, Integrin b 3 (Platelet Glycoprotein IIIa, protein CD61), Integrin b-3, integrin, b 3 (platelet glycoprotein IIIa, antigen CD61), CD51, CD51 protein, CD61, GP3A, GPIIIa, Msk8, Platelet Membrane Glycoprotein IIIa, Vitronectin Receptor a
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Alternative technique
antigenes
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Alternative to gene target
integrin, alpha V, CD51 and MSK8 and VNRA and VTNR, ITGAV and IDBG-77054 and ENSG00000138448 and 3685, transforming growth factor beta binding, Cell surfaces, Itgav and IDBG-184247 and ENSMUSG00000027087 and 16410, ITGAV and IDBG-639711 and ENSBTAG00000019929 and 281875
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