IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)[IL3RB]
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Catalog number
MBS647780
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Price
Please ask
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Size
NA
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Products_type
Antibody
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Reactivity
Mouse, Rat
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Description
Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
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Gene target
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Gene symbol
CSF2RB, IL3, CSF2, IL5, IL36G, IL25, IL22, IL18, IL37, IL6R
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Short name
IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)[IL3RB]
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Host
Rabbit
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Alternative name
IL3RB (CD131, Cytokine Receptor Common functionnal sequence b, CDw131, GM-CSF/Interleukin-3/Interleukin-5 Receptor Common b functionnal sequence, colony stimulating factor 2 receptor, b, low-affinity (granulocyte-macrophage), IL5RB)[IL3RB]
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Alternative to gene target
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), CD131 and CDw131 and IL3RB and IL5RB and SMDP5, CSF2RB and IDBG-6178 and ENSG00000100368 and 1439, protein binding, Plasma membranes, CSF2RB and IDBG-638112 and ENSBTAG00000009064 and 528530
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Gene info
Gene info
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Identity
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Gene
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Long gene name
interleukin 3
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Synonyms gene name
- interleukin 3 (colony-stimulating factor, multiple)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
interleukin 5
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Synonyms gene name
- interleukin 5 (colony-stimulating factor, eosinophil)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 25
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Synonyms gene
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-01-26
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
interleukin 18
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Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 37
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 7 (zeta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 6 receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
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VEGA ID
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