IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)
-
Catalog numberMBS647780
-
PricePlease ask
-
Size5x0.05 mg
-
-
Products_typeAntibody
-
Products_short_name[IL3RB]
-
Products_name_syn[Anti -IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)]
-
Other_names[interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class 2 subunit beta; interleukin-3 receptor class 2 subunit beta; IL-3R class 2 subunit beta; IL-3 receptor class 2 subunit beta; interleukin-3 receptor class II beta chain; colony-stimulating factor 2 receptor subunit beta-2; colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage); Colony-stimulating factor 2 receptor subunit beta-2; Interleukin-3 receptor class II beta chain]
-
Other_gene_names[Csf2rb2; Csf2rb2; Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb; Ai2ca; Il3r; Il3rb2; IL-3 receptor class 2 subunit beta]
-
ClonalityPolyclonal
-
ReactivityMouse, Rat
-
SpecificityRecognizes human CSF2RB/CD131. Species Crossreactivity: Mouse, rat.
-
PurityAffinity Purified Purified by immunoaffinity chromatography.
-
FormSupplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
-
Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
-
Tested_applicationELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
-
DescriptionCytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
GeneGranulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
-
Gene target
-
Gene symbolCSF2RB, IL3, CSF2, IL5, IL36G, IL25, IL22, IL18, IL37, IL6R
-
Short nameIL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)
-
HostRabbit
-
IsotypeIgG
-
Alternative nameIL3RB (CD131, Cytokine Receptor Common functionnal sequence b, CDw131, GM-CSF/Interleukin-3/Interleukin-5 Receptor Common b functionnal sequence, colony stimulating factor 2 receptor, b, low-affinity (granulocyte-macrophage), IL5RB)
-
Alternative to gene targetcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), CD131 and CDw131 and IL3RB and IL5RB and SMDP5, CSF2RB and IDBG-6178 and ENSG00000100368 and 1439, protein binding, Plasma membranes, CSF2RB and IDBG-638112 and ENSBTAG00000009064 and 528530
-
Gene info
-
Identity
-
Gene
-
Long gene namecolony stimulating factor 2 receptor subunit beta
-
Synonyms gene
-
Synonyms gene name
- colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
- colony stimulating factor 2 receptor beta common subunit
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1991-08-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibronectin type III domain containing
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 3
-
Synonyms gene name
- interleukin 3 (colony-stimulating factor, multiple)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecolony stimulating factor 2
-
Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 5
-
Synonyms gene name
- interleukin 5 (colony-stimulating factor, eosinophil)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 36 gamma
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 9
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 25
-
Synonyms gene
-
Synonyms gene name
- interleukin 17E
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-01-26
-
Pubmed identfication
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 22
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-03-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 18
-
Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1997-07-25
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 37
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 7 (zeta)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 6 receptor
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
-
VEGA ID