- Catalog numberMBS622986
- Product nameAnti - BACE, Asp2 (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
- Size5x0.1 mg
- PriceAsk For Price
- Products typeAntibody
- Products short name[BACE, Asp2]
- Products name syn[BACE, Asp2 (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)]
- ClonalityPolyclonal
- IsotypeIgG
- HostHost: Rabbit Source: Human
- ReactivityHuman
- SpecificityThe human peptide sequence has high degree of homology (94%) with mouse and rat BACE/Asp2. No significant sequence homology exists with BACE2/Aps1, a homolog of BACE, or other Asps. Antibody crossreactivity in various species is not established. Control peptides, because of their low MW (
- PurityPurified over the peptide-Sepharose column
- FormAffinity Purified Supplied as a liquid in PBS, pH 7.4 and 0.1% BSA, 0.1% sodium azide, 40% glycerol.
- Concentration1mg/ml
- Storage stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Tested applicationELISA, Western Blot
- Alternative to gene target
- [ "amyloid beta (A4) precursor protein", "AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2", "APP and IDBG-1100 and ENSG00000142192 and 351", "growth factor receptor binding", "nuclei", "App and IDBG-172954 and ENSMUSG00000022892 and 11820", "APP and IDBG-630293 and ENSBTAG00000017753 and 280722" ]
- Gene target- BACE Asp2 Memapsin2 Beta-site APP Cleaving Aspartyl Protease 2
- Identity:HGNC:55075
- Gene:APP-DT
- Long gene name:APP divergent transcript
- Discovery year:2020-06-12
- Classification:Divergent transcripts
- Identity:HGNC:933
- Gene:BACE1
- Long gene name:beta-secretase 1
- Synonyms gene name:beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1
- Discovery year:1999-10-29
- Entrez gene record:23621
- Pubmed identification:10531052
- Classification:Peptidase family A1
- VEGA ID:OTTHUMG00000160636
- Identity:HGNC:620
- Gene:APP
- Long gene name:amyloid beta precursor protein
- Synonyms gene name:Alzheimer disease, amyloid beta (A4) precursor protein
- Synonyms:alpha-sAPP,
- Discovery year:1986-01-01
- Entrez gene record:351
- Pubmed identification:1679289
- RefSeq identity:NM_000484
- Classification:Receptor ligands
- VEGA ID:OTTHUMG00000078438
- Identity:HGNC:8557
- Gene:PABPC4
- Long gene name:poly(A) binding protein cytoplasmic 4
- Synonyms gene name:poly(A)-binding protein, cytoplasmic 4 (inducible form), poly(A) binding protein, cytoplasmic 4 (inducible form)
- Synonyms:iPABP, APP-1
- Discovery year:1999-12-17
- Entrez gene record:8761
- Pubmed identification:10543404
- RefSeq identity:NM_001135653
- Classification:RNA binding motif containing, Small nucleolar RNA protein coding host genes
- VEGA ID:OTTHUMG00000009097
- Identity:HGNC:621
- Gene:NAE1
- Long gene name:NEDD8 activating enzyme E1 subunit 1
- Synonyms gene name:amyloid beta precursor protein binding protein 1, 59kDa
- Synonyms:ula-1APP-BP1
- Discovery year:1999-01-13
- Entrez gene record:8883
- Pubmed identification:8626687, 12740388
- RefSeq identity:NM_003905
- Classification:Ubiquitin like modifier activating enzymes
- VEGA ID:OTTHUMG00000137513
- Gene symbolAPP-DT, BACE1, APP, PABPC4, NAE1
- isotype filter
- IgG
- Short nameAnti - BACE, Asp2 (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
- technique filter
- Enzyme
- anti
- TechniqueEnzyme, anti, antibody to, enzymes
- Alternative techniqueenzymes, antibodies
Gene info
Gene info
Gene info
Locus Specific Databases:Alzheimer Disease & Frontotemporal Dementia Mutation Database