IGF-1R, Active Human recombinant protein
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Catalog numberGWB-AF1F98
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PricePlease ask
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Size1 vial
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Storage temperaturestore cold
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Expiry date1 y
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Categoryresearch antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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DescriptionIGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolIGF1, IGF2, IGFBP1
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Short nameIGF-1R, Active recombinant protein
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TechniqueRecombinant, IGF, igfs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. genways advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameIGF-1R, functionnal H. sapiens Rec. protein
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Alternative techniquerec, igfs
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Gene info
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Identity
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Gene
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Long gene nameinsulin like growth factor 1
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Synonyms gene name
- insulin-like growth factor 1 (somatomedin C)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Neuropeptides
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameinsulin like growth factor 2
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Synonyms gene
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Synonyms gene name
- chromosome 11 open reading frame 43
- insulin-like growth factor 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Neuropeptides
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameinsulin like growth factor binding protein 1
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Synonyms gene
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Synonyms gene name
- insulin-like growth factor binding protein 1
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-11-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Insulin like growth factor binding proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data