IGF I protein
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Catalog number30R-2473
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PricePlease ask
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Size20 µg
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CategoryProteins
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Antibody SubtypeRecombinant Proteins
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Area of researchCytokines & Growth Factors
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ReactivityMouse
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Type of proteinRecombinant
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Expression SystemEscherichia coli
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Grade PurityGrater than 98% pure
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Method of PurificationIGF I protein was purified using a a proprietary chromatographic technique.
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Form BufferProvided in lyophilized form with no additives
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StorageStore at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
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Shipping conditionsBlue Ice
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BioactivityThe ED50 as determined by cell proliferation assay using FDC-P1 cells is < 20 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg For most in vitro applications, the IGF-I exerts its biological activity in the concentration range of 1 to 20 ng/ml
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DescriptionIGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
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Gene target
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Gene symbolPGGT1B, FABP6
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Short nameIGF I protein
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TechniqueIGF, igfs
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Alternative namePurified recombinant Mouse IGF I protein
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Alternative techniqueigfs
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Gene info
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Identity
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Gene
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Long gene nameprotein geranylgeranyltransferase type I subunit beta
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Synonyms gene name
- protein geranylgeranyltransferase type I, beta subunit
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Synonyms
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Locus
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Discovery year1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefatty acid binding protein 6
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Synonyms gene name
- fatty acid binding protein 6, ileal
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-09-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fatty acid binding protein family
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VEGA ID