IGF BP3 protein

• Catalog number
  30R-AI122
• Price
  Please ask
• Size
  25 µg

• Category
  Proteins
• Antibody Subtype
  Recombinant Proteins
• Area of research
  Cytokines & Growth Factors
• Reactivity
  Human
• Residues
  Region of IGF BP3 protein corresponding to amino acids GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK.
• Type of protein
  Recombinant
• Expression System
  Escherichia coli
• Grade Purity
  Grater than 98% pure
• Form Buffer
  Lyophilized from 20 mM NaCl. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.
• Storage
  Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• Shipping conditions
  Blue Ice
• Tested for
  Please refer to the datasheet
• Bioactivity
  The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 for this effect is approximately 0.2 ug/ml in presence of 15 ng/ml of human IGF-II.
• URL
• More info
• Description
  IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.

• Gene target
  BP3   protein  
• Gene symbol
  EIF4EBP3, ANKHD1-EIF4EBP3, HS1BP3
• Short name
  IGF BP3 protein
• Technique
  IGF, igfs
• Alternative name
  Purified recombinant Human IGF BP3 protein
• Alternative technique
  igfs

Gene info

• Identity
  HGNC:3290
• Gene
  EIF4EBP3
• Long gene name
  eukaryotic translation initiation factor 4E binding protein 3
• Synonyms
  • 4E-BP3
• GenBank acession
  • AF038869
• Locus
  5q31.3
• Discovery year
  1998-11-18
• Entrez gene record
  8637
• Pubmed identfication
  • 9593750
• RefSeq identity
  • NM_003732
• VEGA ID
  OTTHUMG00000129498

Gene info

• Identity
  HGNC:33530
• Gene
  ANKHD1-EIF4EBP3
• Long gene name
  ANKHD1-EIF4EBP3 readthrough
• Synonyms
  • MASK-BP3
• GenBank acession
  • AF521883
• Locus
  5q31.3
• Discovery year
  2007-07-31
• Entrez gene record
  404734
• Pubmed identfication
  • 16297570
  • 14557257
• RefSeq identity
  • NM_020690
• VEGA ID
  OTTHUMG00000166212

Gene info

• Identity
  HGNC:24979
• Gene
  HS1BP3
• Long gene name
  HCLS1 binding protein 3
• Synonyms
  • HS1-BP3
  • FLJ14249
• Locus
  2p24.1
• Discovery year
  2006-08-15
• Entrez gene record
  64342
• Pubmed identfication
  • 10590261
  • 15699368
• RefSeq identity
  • NM_022460
• VEGA ID
  OTTHUMG00000122099

Similar products