Recombinant Mouse Interleukin-23/IL-23 Protein 50µg
-
Catalog numberPKSM041087-50µg
-
PricePlease ask
-
Size50µg
-
-
ActivityNA
-
SynonymSGRF;IL-23p19;CLMF p40;IL-12 subunit p40;NKSF2
-
SequenceVal22-Ala196&Met23-Ser335
-
Fusion tagNA
-
AccessionQ9EQ14&P43432
-
Expressed HostHuman Cells
-
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
-
Purity＞95% as determined by reducing SDS-PAGE.
-
Stability and StorageLyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
-
Mol Mass19.7&35.8 kDa
-
AP Mol Mass40-55 kDa
-
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
-
BackgroundInterleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
SourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolIL23A, IL22, IGHV3-23, IGKV2D-23, SNORD116-23, SNORD114-23, SNORD115-23, IGKV2-23, ERVW-23, IGLV2-23
-
Short nameRecombinant Mouse Interleukin-23/IL-23 Protein 50µg
-
TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Hostmouse
-
SpeciesMouse, Mouses
-
Alternative nameRec. Mouse Interleukin-23/Interleukin-23 Protein 50µg
-
Alternative techniquerec, murine
-
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 23 subunit alpha
-
Synonyms gene name
- interleukin 23, alpha subunit p19
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-04-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 22
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-03-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable 3-23
-
GenBank acession
-
Locus
-
Discovery year2000-04-04
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 2D-23 (pseudogene)
-
Synonyms gene name
- immunoglobulin kappa variable 2D-23
- immunoglobulin kappa variable 2D-23 pseudogene
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin kappa locus at 2p11.2
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesmall nucleolar RNA, C/D box 116-23
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2007-02-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Small nucleolar RNAs, C/D box
Gene info
-
Identity
-
Gene
-
Long gene namesmall nucleolar RNA, C/D box 114-23
-
Synonyms
-
Locus
-
Discovery year2006-09-26
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Small nucleolar RNAs, C/D box
Gene info
-
Identity
-
Gene
-
Long gene namesmall nucleolar RNA, C/D box 115-23
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2007-02-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Small nucleolar RNAs, C/D box
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 2-23 (pseudogene)
-
Synonyms gene name
- immunoglobulin kappa variable 2-23
- immunoglobulin kappa variable 2-23 pseudogene
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin kappa locus at 2p11.2
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameendogenous retrovirus group W member 23
-
Synonyms gene name
- endogenous retrovirus group W, member 23
-
GenBank acession
-
Locus
-
Discovery year2013-10-21
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin lambda variable 2-23
-
GenBank acession
-
Locus
-
Discovery year2000-05-08
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin lambda locus at 22q11.2
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
