2-NP

CAT: 0804-HY-W013523-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W013523-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells[1].
CAS Number
[65182-56-1]
UNSPSC
12352005
Hazard Statement
H302, H318
Target
HSV; JAK; STAT
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/2-np.html
Purity
99.89
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=CC=C1C2=NC3=NC=CC=C3C=C2
Molecular Formula
C14H10N2O
Molecular Weight
222.25
Precautions
H302, H318
References & Citations
[1]Lynch RA, et, al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67 (3) :1254-61.|[2]Luo N, et al., Up-regulated Lnc BTU promotes the production of duck plague virus DNA polymerase and inhibits the activation of JAK-STAT pathway to facilitate duck plague virus replication. Poult Sci. 2024 Dec;103 (12) :104238.|[3]Wang Y, et al., A small-molecule enhancer of STAT1 affects herpes simplex keratitis prognosis by mediating plasmacytoid dendritic cells migration through CXCR3/CXCL10. Int Immunopharmacol. 2025 Feb 6;147:113959.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-NP206-01NP-CGG
HY-129496-01NP-313
HY-W169940NP-184
HY-NP133NP-KLH
HY-163540-01NP-BTA
HY-19053NP-252
HY-NP141-01NP-BSA
HY-163017NP-5497-KA
HY-178366PAC/NP-IN-1
HY-145882BOD-NH-NP

Alternative Products

CatalogName
M15475-012-NP
ABL-TC0482NP 2
TRC-N894950-100MG2-NP-AMOZ
sc-2882702-NP-AHD
MF-0056165-012-NP-AOZ
A10F63-2Recombinant PIV-2 NP

Popular Products