2-NP

• UNSPSC Description:

  2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells[1].

• Target Antigen:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-np.html

• Purity:

  99.89

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  OC1=CC=CC=C1C2=NC3=NC=CC=C3C=C2

• Molecular Weight:

  222.247

• References & Citations:

  [1]Lynch RA, et, al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  65182-56-1