FAUC 346

• Description:

  FAUC 346, a highly selective D3 partial agonist (EC50 = 1.5 nM) [1][2].

• UNSPSC:

  12352005

• Target:

  Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/fauc-346.html

• Purity:

  99.90

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC2=CC=CC=C2S1)NCCCCN3CCN(C4=CC=CC=C4OC)CC3

• Molecular Formula:

  C24H29N3O2S

• Molecular Weight:

  423.57

• References & Citations:

  [1]Bertrand Kuhnast, et al. Synthesis and radiolabeling of N-[4-[4- (2-[11C]methoxyphenyl) piperazin-1-yl]butyl]benzo[b]thiophene-2-carboxamide -- a potential radiotracer for D3 receptor imaging with PET. Nucl Med Biol. 2006 Aug;33 (6) :785-95.|[2]Carsten Hocke, et al. 18F-Labeled FAUC 346 and BP 897 derivatives as subtype-selective potential PET radioligands for the dopamine D3 receptor. ChemMedChem. 2008 May;3 (5) :788-93.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  D3 Receptor

• CAS Number:

  474432-65-0