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FAUC 213

CAT: 0804-HY-14327-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14327-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. FAUC 213 has less activity on D2 and D3 receptors (Kis of 3.4 μM, 5.3 μM for hD2, hD3, respectively) . FAUC 213 can cross the blood-brain barrier (BBB) . FAUC 213 exhibits atypical antipsychotic characteristic[1].
CAS Number
337972-47-1
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fauc-213.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(C=C1)=CC=C1N(CC2)CCN2CC3=NN4C=CC=CC4=C3
Molecular Formula
C18H19ClN4
Molecular Weight
326.82
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Frank Boeckler, et al. FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. Psychopharmacology (Berl) . 2004 Aug;175 (1) :7-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor; D3 Receptor; D4 Receptor

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