CAY10502

CAT: 0804-HY-116301-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-116301-01Size:1 mg
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Description
CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases[1][2][3].
CAS Number
[888320-29-4]
Product Name Alternative
MLN7243
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H319-H332
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cay10502.html
Purity
99.0
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CN(CC(COC2=CC=C(OCCCCCCCCCC)C=C2)=O)C3=C1C=C(C(O)=O)C=C3)OC
Molecular Formula
C30H37NO7
Molecular Weight
523.62
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Pohjala L L, et al. Interference by bovine serum albumin in PED6 based phospholipase A2 screening assays[J]. Die Pharmazie, 2012.|[2]Barnett JM, et al. Role of cytosolic phospholipase A (2) in retinal neovascularization. Invest Ophthalmol Vis Sci. 2010;51 (2) :1136-1142.|[3]Cui Y, et al. Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway. Cell Calcium. 2014 Jan;55 (1) :48-58.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A

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