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FIDAS-5

CAT: 0804-HY-136144-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136144-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1].
CAS Number
1391934-98-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fidas-5.html
Purity
98.46
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CNC1=CC=C(/C=C/C2=C(F)C=CC=C2Cl)C=C1
Molecular Formula
C15H13ClFN
Molecular Weight
261.72
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang W, et al. Fluorinated N, N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A. ACS Chem Biol. 2013 Apr 19;8 (4) :796-803.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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