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8-Bromoadenine

CAT: 0804-HY-W076740-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W076740-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium[1][2].
CAS Number
6974-78-3
Product Name Alternative
8-Bromo-9H-purin-6-amine
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; DNA/RNA Synthesis
Type
Biochemical Assay Reagents
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-bromoadenine.html
Purity
98.92
Solubility
0.1 M NaOH : 0.2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
BrC1=NC2=C(N1)C(N)=NC=N2
Molecular Formula
C5H4BrN5
Molecular Weight
214.03
Precautions
H302, H315, H319, H335
References & Citations
[1]Tkalich A V, et al. Effect of 8-bromoadenine on DNA repair[J]. Tsitologiia, 1980, 22 (8) : 994-997.|[2]Radioactively marked nucleic acid units. German Democratic Republic, DD106383 A1 1974-06-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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