8-Bromoadenine

• UNSPSC Description:

  8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium[1][2].

• Target Antigen:

  Biochemical Assay Reagents; DNA/RNA Synthesis

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Cell Cycle/DNA Damage;Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/8-bromoadenine.html

• Purity:

  97.14

• Solubility:

  10 mM in DMSO

• Smiles:

  BrC1=NC2=C(N1)C(N)=NC=N2

• Molecular Weight:

  214.026

• References & Citations:

  [1]Tkalich A V, et al. Effect of 8-bromoadenine on DNA repair[J]. Tsitologiia, 1980, 22(8): 994-997.|[2]Radioactively marked nucleic acid units. German Democratic Republic, DD106383 A1 1974-06-12.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  6974-78-3