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8-Bromoadenosine

CAT: 0804-HY-W013195-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W013195-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. 8-Bromoadenosine can quench the intrinsic fluorescence of human serum albumin (HSA) through static quenching procedure. 8-Bromoadenosine can be used to synthesize adenosine phosphate, such as Acadesine , Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[2].
CAS Number
2946-39-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-bromoadenosine.html
Concentration
10mM
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@@H]1CO
Molecular Formula
C10H12BrN5O4
Molecular Weight
346.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.|[2]Cui, F., (2009) . Characterization of the interaction between 8-bromoadenosine with human serum albumin and its analytical application. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 74 (4), 964–971.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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