Aβ-IN-8

• Description :

  Aβ-IN-8 (compound 7e) is a potent inhibitor of the Aβ aggregation[1].

• UNSPSC :

  12352005

• Target :

  Amyloid-β

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/aβ-in-8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C=C(/C=N/C2=NC3=CC=C(OC(F)(F)F)C=C3S2)N(C)C=C1OCC4=CC=CC=C4

• Molecular Formula :

  C22H16F3N3O3S

• Molecular Weight :

  459.44

• References & Citations :

  [1]Mohammad Hossein Asgarshamsi, et al. Synthesis of Some Benzothiazole Derivatives Based on 3-Hydroxypyridine-4-one and Benzaldehyde and Evaluation of Their β-Amyloid Aggregation Inhibition Using both Experimental Methods and Molecular Dynamic Simulation. Chem Biodivers. 2023 Sep 10:e202301113.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported