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DEPTOR-IN-1

CAT: 0804-HY-132902-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132902-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DEPTOR-IN-1 is a novel putative DEPTOR inhibitor with a Kd value of 9.3 μM.
CAS Number
2615911-12-9
UNSPSC
12352005
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/deptor-in-1.html
Purity
99.09
Solubility
DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=CC=C3OCN(CC3=C2OC(C4=CC(Cl)=C(C=C4)Cl)=C1O)CC5=CC(F)=CC=C5
Molecular Formula
C24H16Cl2FNO4
Molecular Weight
472.29
References & Citations
[1]Hou Y, et al. Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. J Med Chem. 2021 Oct 28;64 (20) :14942-14954.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported