hGPR91 antagonist 3

• UNSPSC Description:

  hGPR91 antagonist 3 (Compound 5g) is a potent and orally active GPR91 antagonist with IC50s of 35 nM and 135 nM, for human GPR91 and rat GPR91, respectively[1].

• Target Antigen:

  Succinate Receptor 1

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/hgpr91-antagonist-3.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  O=C(CCCC1=CC=C2C=CC=NC2=N1)NCC3=CC(C4=CC(C(F)(F)F)=C(F)C=C4)=NO3

• Molecular Weight:

  458.41

• References & Citations:

  [1]Bhuniya D, et al. Discovery of a potent and selective small molecule hGPR91 antagonist. Bioorg Med Chem Lett. 2011;21(12):3596-3602.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1314796-31-0