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4β-Hydroxywithanolide E

CAT: 0804-HY-N7661Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N7661Size:1 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4β-Hydroxywithanolide E, isolated from Physalis peruviana L., inhibits adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion. 4β-Hydroxywithanolide E is an adipogenesis inhibitor and inhibits PPARγ, C/EBPα, and the adipocyte-specific molecule aP2 mRNA expression[1].
CAS Number
[54334-04-2]
UNSPSC
12352005
Target
PPAR
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/4β-hydroxywithanolide-e.html
Solubility
10 mM in DMSO
Smiles
C[C@]1(C2=O)[C@@]3([C@H](C=C2)O)[C@](C[C@]([C@@]4(CC[C@](O)5[C@@](O)([C@@](OC6=O)([H])CC(C)=C6C)C)O)([H])[C@]1([H])CC[C@@]45C)([H])O3
Molecular Formula
C28H38O8
Molecular Weight
502.60
References & Citations
Physalis peruviana
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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