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17alpha-Hydroxywithanolide D

CAT: 0804-HY-170325Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170325Size:1 Each
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Description
17alpha-Hydroxywithanolide D is the allosteric modulator for NMDA receptor with an IC50 of 44.24 nM. 17alpha-Hydroxywithanolide D exhibits neuroprotective activity and can be used in research of Alzheimer's disease disease[1].
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
CC1[C@@H](C)C(O)O[C@@H]([C@](O)([C@@]2(O)CC[C@@H]3[C@]2(C)CC[C@H]4[C@H]3C[C@@H]5[C@@]6(O5)[C@]4(C)[C@H](O)CC[C@@H]6O)C)C1
Molecular Formula
C28H46O7
Molecular Weight
494.66
References & Citations
[1]Vashisth MK, et al., In-Silico discovery of 17alpha-hydroxywithanolide-D as potential neuroprotective allosteric modulator of NMDA receptor targeting Alzheimer's disease. Sci Rep. 2024 Nov 13;14 (1) :27
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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