p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09]

p18 INK4c Recombinant Rabbit Monoclonal Antibody [JE36-09]

• Description: Cyclin-dependent kinase 4 inhibitor C is an enzyme that in humans is encoded by the CDKN2C gene. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
• Product Name Alternative: CDK6 inhibitor p18 antibody CDKN 2C antibody CDKN 6 antibody Cdkn2c antibody CDKN6 antibody CDN2C_HUMAN antibody Cyclin dependent inhibitor antibody Cyclin dependent kinase 4 inhibitor C antibody Cyclin dependent kinase 6 inhibitor antibody Cyclin dependent kinase 6 inhibitor p18 antibody Cyclin dependent kinase inhibitor 2C (p18 inhibits CDK4) antibody Cyclin dependent kinase inhibitor 2C antibody Cyclin-dependent kinase 4 inhibitor C antibody Cyclin-dependent kinase 6 inhibitor antibody INK4C antibody OTTHUMP00000046546 antibody p18 antibody p18 inhibits CDK4 antibody p18 INK4c antibody p18 INK6 antibody p18-INK4c antibody p18-INK6 antibody
• Abbreviation: CDKN2C, CDKN6
• CAS Number: 9000-83-3
• Swiss Prot: P42773 Human, Q60772 Mouse,
• Cellular Locus: Cytoplasm, cytosol, nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human p18 INK4c aa 1-150 / 168.
• Isotype: IgG
• Clone: JE36-09
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: HeLa cell lysate, 293T cell lysate, MCF7 cell lysate, A549 cell lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, human skeletal muscle tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:500
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 18 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes