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SB-366791

CAT: 0804-HY-12245-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: HY-12245-01Size: 5 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB-366791 is a potent and selective vanilloid receptor (VR1/TRPV1) antagonist (IC50=5.7 nM) . SB-366791 can be used for the research of inflammation[1][2].
CAS Number
[472981-92-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/SB-366791.html
Purity
98.11
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=CC=CC(OC)=C1)/C=C/C2=CC=C(Cl)C=C2
Molecular Formula
C16H14ClNO2
Molecular Weight
287.74
Precautions
H302, H315, H319, H335
References & Citations
[1]Lappin SC, et al. TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation. Eur J Pharmacol. 2006;540 (1-3) :73-81.|[2] Gunthorpe MJ, et al. Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist [published correction appears in Neuropharmacology. 2004 May;46 (6) :905]. Neuropharmacology. 2004;46 (1) :133-149.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPV1

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