SB-423562

• Description :

  SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research.

• CAS Number :

  [351490-27-2]

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  CaSR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/SB-423562.html

• Purity :

  99.66

• Solubility :

  DMSO : 5 mg/mL (ultrasonic)

• Smiles :

  OC(CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC(C=CC=C3)=C3C2)=C1)=O

• Molecular Formula :

  C26H32N2O4

• Molecular Weight :

  436.54

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Kumar S, et al. An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation. Bone. 2010 Feb;46 (2) :534-42.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2