SB-423562

• UNSPSC Description:

  SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research.

• Target Antigen:

  CaSR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/SB-423562.html

• Solubility:

  DMSO : 5 mg/mL (ultrasonic)

• Smiles:

  OC(CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC(C=CC=C3)=C3C2)=C1)=O

• Molecular Weight:

  436.54

• References & Citations:

  [1]Kumar S, et al. An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation. Bone. 2010 Feb;46(2):534-42.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Phase 2

• CAS Number:

  351490-27-2