Pep2-8

Pep2-8

• CAS Number: 1541011-97-5
• UNSPSC Description: Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM[1].
• Target Antigen: PCSK9
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pep2-8.html
• Purity: 99.74
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(N[C@H](C(N)=O)C(C)C)[C@@H](NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@]([C@H](O)C)([H])NC([C@@H](NC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC(C)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56
• Molecular Weight: 1715.85
• References & Citations: [1]Yingnan Zhang, et al. Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J Biol Chem. 2014 Jan 10;289(2):942-55.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported