Pep2-EVKI

• Description:

  Pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression[1].

• Product Name Alternative:

  YNVYGIEEVKI

• UNSPSC:

  12352209

• Target:

  PKC

• Type:

  Peptides

• Related Pathways:

  Epigenetics; TGF-beta/Smad

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pep2-evki.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@@H](N)CC2=CC=C(O)C=C2)=O)=O)=O

• Molecular Formula:

  C62H95N13O19

• Molecular Weight:

  1326.49

• References & Citations:

  [1]Akira Terashima, et al. Regulation of synaptic strength and AMPA receptor subunit composition by PICK1. J Neurosci. 2004 Jun 9;24 (23) :5381-90.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [1315378-67-6]